Amino-caprolactam derivatives as gamma-secretase inhibitors.
نویسندگان
چکیده
A series of amino-caprolactam sulfonamides were developed from a screening hit. Compounds with good in vitro and in vivo gamma-secretase activity are reported.
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عنوان ژورنال:
- Bioorganic & medicinal chemistry letters
دوره 17 21 شماره
صفحات -
تاریخ انتشار 2007